Drospirenone will increase the amount or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar. crofelemer will increase amounts of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Crofelemer has the potential to inhibit CYP3A4 at concentrations envisioned inside the gut; unlikely to inhibit syst... https://hagueapotheek.com/product/diazepam-kopen/